Makhosi completed his BSc degree in applied maths and physics at University of Zululand in 2001. He taught maths and science in public schools under Hlabisa district as a temporary teacher. He graduated with a BSc (Hons) degree in applied physics and MSc in NMR Spectroscopy (condensed-matter physics) at UKZN in 2008 and Wits University in 2012, respectively.
In 2014 he joined the South African National Space Agency (SANSA) as a PDP PhD researcher. His PhD project is focussed primarily on modelling equatorial/low- latitude plasma dynamics in the African sector. During his time at SANSA he has attended and presented his work at several national and international conferences.